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The French Paradox is a phenomenon that people in France, who have highest consumption of red wine per person, have the lowest cardiovascular mortality rate and one of the longest in longevity in the Western world. One of the key molecules behind this is a grape flavonoid molecule trans-Resveratrol, t-RSV.

Numerous experimental laboratory studies of this molecule have generated promising results for potential applications of t-RSV from prevention and treatment of numerous diseases such as diabetes, cardiovascular pathologies and cancer, to use in anti-ageing products.

However, studies in humans have so far not provided convincing evidence of clinical benefits of t-RSV. This frustration has been attributed to the fact that when this molecule is used not as a part of red wine, but in its isolated form, it gets modified by the factors of the gastro-intestinal tract, GIT, and loses its metabolic activity.

To circumvent this problem the...

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